5 edition of Amyotrophic lateral sclerosis found in the catalog.
Includes bibliographical references and index.
|Statement||Hiroshi Mitsumoto and Theodore L. Munsat, editors.|
|Contributions||Mitsumoto, Hiroshi., Munsat, Theodore L., 1930-|
|LC Classifications||RC406.A24 M58 2001|
|The Physical Object|
|Pagination||xiii, 451 p. :|
|Number of Pages||451|
|LC Control Number||2001270396|
Find a neurologist and care team. Here we will focus on clinical and pre-clinical SC trials in the last 5 years. Researchers continue to study possible causes of ALS. It does not repair the damage already done to the body, but it appears to be modestly effective in prolonging the survival of people with ALS.
Please try again. Future research Future research implications include additional research on stem cells. Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. Smoking is the only likely environmental risk factor for ALS.
Obviously, being an edited collection with several contributors, this book is replete with the problems common to all such anthologies. ALS affects people all over the world and of all ethnic backgrounds. They found GF delivery to mid-stage SOD1 rodents showed increased neuromuscular connections, and a lifespan increase of 28 days, possibly due to reduced neuronal loss. Studies indicate that people who have served in the military are at higher risk of ALS. Sufferers experience many psychological symptoms as secondary effects from the physiological damage which occurs. Inresearchers identified a link between ALS and chromosome
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So although the majority of ALS cases occur from causes unknown, a select few cases can be explained by genetic mutation. Inresearchers identified a link between ALS and chromosome Unfortunately, there is little on physical rehabilitation, an important topic for all those who manage chronic diseases of the motor system.
The goal is to increase the availability of, and access to, high quality specimens for research to understand the neurological basis of the disease. Guanabenz, an intervention targeted specifically at cell apoptosis has demonstrated an effect on symptoms, speed of progression, and lifespan.
This eventually affects chewing, swallowing, speaking and breathing. Physical Therapy You couldn't ask for a more comprehensive book than this latest volume from Demos Quest.
Environmental factors, such as the following, might trigger ALS.
For example, researchers have suggested that exposure to toxins during warfare, or strenuous physical activity, are possible reasons for why some veterans and athletes may be at increased risk of developing ALS.
Champion Dallas A. New treatment options Potential therapies for ALS are being investigated in a range of disease models.
Neural stem cell-based treatment for neurodegenerative diseases. Atrophy of the cortexes is implicated as a contributor to the presenting deficits of ALS Mioshi, Additional concerns for this treatment include the political implications of this treatment as some political groups disagree with stem cell research as a whole.
People may choose to be fully informed about these considerations and the long-term effects of life without movement before they make decisions about ventilation support.
SCs continue to have vast potential, and when combined with GFs have shown encouraging effects on disease progression in rodent models. ALS is often called Lou Gehrig's disease, after the baseball player who was diagnosed with it. There are several techniques to help people increase forceful coughing, including mechanical cough assist devices and breath stacking.
Exposure to different toxins has been suggested as a potential cause, ranging from occupational exposure and physical activity to military exposure and trauma.
For example, NINDS-supported scientists are currently investigating whether lowering levels of the SOD1 enzyme in the brain and spinal cord of individuals with SOD1 gene mutations would slow the rate of disease progression. A large proportion of future research will center upon investigation of this.
Rather, it is a detailed and factual exposition of many of the important issues facing ALS patients and their families. Additional cortical atrophy was found in frontal and parietal areas of the brain.
In another important discovery was made when scientists found that a defect in the C9ORF72 gene is not only present in a significant subset of individuals with ALS but also in some people with a type of frontotemporal dementia FTD.
The chapters devoted to physician-assisted suicide, euthanasia, and terminal care are undoubtedly timely.
However, some people with ALS live 10 or more years. Although it is still not clear how mutations in the SOD1 gene lead to motor neuron degeneration, there is increasing evidence that the gene playing a role in producing mutant SOD1 protein can become toxic.
Evidence has suggested that certain cases of ALS are inherited while others are developed due to toxins which has helped scientists narrow down the possible mechanisms of action which facilitate this disease.
The exact cause of ALS is not known. To date, over different mutations in SOD1 have been linked with the disorder, some of which such as H46R have a very long clinical course, while others, such as A4Vare exceptionally aggressive.
In ALS, both the upper motor neurons and the lower motor neurons degenerate or die, and stop sending messages to the muscles.Dec 10, · Amyotrophic Lateral Sclerosis: A Patient Care Guide for Clinicians is a practical reference for clinicians caring for ALS patients that brings together the collective wisdom of those at the forefront of patient-oriented research and practice.
The book compiles recent findings of both evidence-based and experience-based research to provide clinicians with tools that improve quality and length Brand: Springer Publishing Company.
Editorial Reviews. Reviewer: Daniel B. Hier, MD (University of Illinois at Chicago College of Medicine) Description: This is the second edition of a guide to amyotrophic lateral sclerosis (ALS) for families and patients.
The book is multi-authored and edited by two distinguished authorities on ALS. Purpose: This book is aimed at giving patients and their families a better understanding of the Author: Hiroshi Mitsumoto.
Navigating Life with Amyotrophic Lateral Sclerosis provides accessible, comprehensive, and up-to-date information about the challenges patients, family members, and caregivers face when confronted by ALS, a disease that affects approximately 5, Americans every year, with as many as 30, people managing the disease at any given time.
Amyotrophic Lateral Sclerosis covers every aspect of the management of ALS, from clinical features of the disease, to diagnosis, to an overview of symptom management.
Major sections deal with medical and rehabilitative management, living with ALS, managing advanced disease, end-of-life issues, and resources that can provide support and 5/5(3). Mar 04, · Amyotrophic Lateral Sclerosis: A Patient Care Guide for Clinicians is a state-of-the-art review of optimal ALS care.
Yet effective organization of clinical care, drawing on a wide variety of allied disciplines, can support patients and families through the course of the disease by maximizing function, limiting excess morbidity, and preparing Author: Steven M.
Albert. Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and the spinal cord. Motor neurons reach from the brain to the spinal cord and from the spinal cord to the muscles throughout the body.
The progressive degeneration of the motor neurons in ALS eventually leads to their death.